Lipid Composition and the Lateral Pressure Profile in Bilayers
نویسندگان
چکیده
منابع مشابه
Methodological problems in pressure profile calculations for lipid bilayers.
From molecular dynamics simulations of a dipalmitoyl-phosphatidyl-choline (DPPC) lipid bilayer in the liquid crystalline phase, pressure profiles through the bilayer are calculated by different methods. These profiles allow us to address two central and unresolved problems in pressure profile calculations: The first problem is that the pressure profile is not uniquely defined since the expressi...
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Cell membranes contain multiple lipid and protein components having heterogeneous in-plane (lateral) distribution. Nanoscale rafts are believed to play an important functional role, but their phase state-domains of coexisting phases or composition fluctuations-is unknown. As a step toward understanding lateral organization of cell membranes, we investigate the difference between nanoscale domai...
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The components of the effective internal lateral pressure arising from the lipid headgroups and the lipid chains in bilayer membranes are deduced from the conditions for interfacial equilibrium and the spontaneous bending moments within the component monolayers. The latter are obtained from the intrinsic curvature that is deduced from X-ray diffraction measurements on the corresponding inverted...
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Isothermal application of hydrostatic pressure to liquid crystalline phospholipid bilayers increases chain segment orientational order and thus chain extension. By using pressure to perturb chain order in single-component bilayers and bilayers comprising a binary mixture of lipids, it is possible to compare the relative influences of intrinsic lipid properties and collective bilayer properties ...
متن کاملLateral pressure profiles in lipid monolayers.
We have used molecular dynamics simulations with coarse-grained and atomistic models to study the lateral pressure profiles in lipid monolayers. We first consider simple oillair and oil/water interfaces, and then proceed to lipid monolayers at air/water and oil/water interfaces. The results are qualitatively similar in both atomistic and coarse-grained models. The lateral pressure profile in a ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1999
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(99)77415-1